Addison’s disease

Addison’s disease Chronic underfunction of the outer portion of the adrenal gland, most commonly due to autoimmune destruction. Other causes include physical trauma to the adrenal gland, hemorrhage, tuberculosis, and destruction of the pituitary gland cells that secrete adrenocorticotropic hormone (ACTH), which normally controls the adrenal gland. Addison’s disease is characterized by bronzing of the skin, anemia, weakness, and low blood pressure.