biological response modifier

biological response modifier A substance that stimulates the body’s response to infection and disease. Abbreviated BRM. The body naturally produces small amounts of certain BRMs. Some BRMs are made in the laboratory in large amounts for use in treating cancer, rheumatoid arthritis, Crohn’s disease, hepatitis, and other diseases. BRMs used in biological therapy include monoclonal antibodies, interferon, interleukin-2 (IL-2), and colony-stimulating factor. Also known as biologics.