IgA nephropathy

IgA nephropathy A chronic disorder caused by the accumulation of immunoglobulin A deposits within the filtering units of the kidney, resulting in the presence of blood and protein in the urine and swelling in the extremities. The disease progresses with time and may ultimately lead to renal failure. High blood pressure is one complication of the disease. The cause is not fully understood, but genetic (inherited) factors may be related to the development of the condition. Treatment involves medications and focuses on slowing the progression of the disease and preventing complications. Also known as Berger disease.