Langerhans cell histiocytosis

Langerhans cell histiocytosis The preferred name for what was once called histiocytosis X. Langerhans cell histiocytosis refers to several disorders in which histiocytes start to multiply and proliferate abnormally. The result can be tissue damage, pain, the development of tumor-like lumps, fatigue, and other symptoms. If histiocytosis affects the pituitary gland, diabetes insipidus may also develop. Treatment includes radiation and chemotherapy; although for reasons unknown, some cases of histiocytosis go into remission without treatment. This disease includes the conditions known as eosinophilic granuloma, Letterer Siwe disease, and Hand-Schuller-Christian disease.