rickets, hypophosphatemic

rickets, hypophosphatemic A rare genetic form of rickets that is characterized by low blood phosphate level (hypophosphatemia), defective intestinal absorption of phosphate, and unresponsiveness to vitamin D. The basic problem in hypophosphatemic rickets is decreased resorption of phosphate by the tubules in the kidney. Females typically have less severe disease than males. The condition is…

rickets

rickets A disease of infants and children that disturbs normal bone formation (ossification), leading to failure to mineralize bone. Rickets softens bone, producing osteomalacia, and permits marked bending and distortion of bones. Other features of rickets include softness of the infant’s skull (craniotabes), enlargement of the front end of the ribs (creating the “rachitic rosary”),…

ribonucleic acid

ribonucleic acid A nucleic acid that is similar to DNA but contains ribose rather than deoxyribose. Abbreviated RNA. RNA, in fact, can form upon a DNA template. The several classes of RNA molecules play important roles in protein synthesis and other cell activities. See also messenger RNA; RNA, ribosomal; RNA, transfer.

rib

rib One of the 12 paired arches of bone that form the skeletal structure of the chest wall (the rib cage). The ribs attach to the vertebrae of the spine in the back. The 12 pairs of ribs consist of 7 pairs of ribs that attach to the sternum in the front and are known…