progeria

progeria One of a group of rare genetic disorders that causes premature aging in children. The classic type of progeria is Hutchinson-Gilford progeria syndrome, which is characterized by dwarfism, baldness, pinched nose, small face and small jaw relative to the head size, delayed tooth formation, aged-looking skin, stiffness of joints, hip dislocations, arteriosclerosis, and heart…

proctitis

proctitis Inflammation of the rectum. Proctitis may be due to a considerable number of causes, including infectious agents and ulcerative colitis. Infectious proctitis is often due to agents such as Chlamydia trachomatis, Neisseria gonorrheae, and herpes simplex virus, all of which can be acquired during anoreceptive intercourse. Proctitis is also a hallmark of ulcerative colitis,…

probiotic

probiotic A substance that appears to replenish or support the growth of helpful bacteria in the intestinal tract. The most common probiotic is acidophilus, which is present in yogurt, in acidophilus milk, and in supplements. As the name indicates, probiotics have been developed to counter one unfortunate effect of treatment with antibiotics: the decimation of…

probe

probe 1 In surgery, a slender, flexible rod with a blunt end that is used to explore. 2 In molecular genetics, a labeled bit of DNA or RNA that is used to find its complementary sequence or to locate a particular clone.

proband

proband The family member through whom a family’s medical history comes to attention. For example, a proband might be a baby with Down syndrome. The proband may also be called the index case, propositus (if male), or proposita (if female).