portal hypertension

portal hypertension An elevated pressure in the veins of the portal circulation. Normally, the veins from the stomach, intestine, spleen, and pancreas merge into the portal vein, which then branches into smaller vessels and travels through the liver. If the vessels in the liver are blocked, it is hard for the blood to flow, causing…

porphyria

porphyria One of a variety of hereditary diseases that are characterized by abnormalities in the reactions needed for the production of heme, an essential substance for the body, resulting in increased formation and excretion of chemicals called porphyrins. Most porphyrias affect the skin or the nervous system. Attacks may range from mild to severe. Besides…

Pompe disease

Pompe disease An inherited deficiency of the enzyme alpha-glucosidase which helps the body break down glycogen, a complex carbohydrate that is converted to glucose for energy. Without the enzyme, glycogen builds up in the heart and other muscles, causing extensive damage. There are several different forms of Pompe disease which vary in severity. Pompe disease…

polysomnography

polysomnography Electronic monitoring of a sleeping patient to look for abnormalities in sleep patterns and/or brain waves. Polysomnography correlates electroencephalogram readings with observation of the patient. Usually, respiration, oxygen saturation, body position, and other factors are also measured during polysomnography. See also sleep apnea; sleep apnea, central; sleep apnea, obstructive; sleep disorders.