nondisjunction

nondisjunction Failure of paired chromosomes to separate (to disjoin) during cell division, so that both chromosomes go to one daughter cell and none go to the other. Nondisjunction causes errors in chromosome number, such as trisomy 21 (Down syndrome) and monosomy X (Turner syndrome). It is also a common cause of early spontaneous abortions.

nodule

nodule A small collection of tissue that is palpable (can be felt) at any level of the skin (in the epidermis, dermis, or subcutis) or in another tissue of the body. Nodules characteristically range in size from 1 to 2 cm in diameter.