ichthyosis vulgaris

ichthyosis vulgaris A genetic skin disease characterized by scaly areas of skin that usually appear in childhood. The palms and soles are often affected. Areas that tend to be spared include the armpits, the insides of the elbows, and the skin behind the knee. Many people with ichthyosis vulgaris also have asthma, eczema, or hay…

I-cell disease

I-cell disease A rare, severe genetic disorder of the lysosomes (organelles within a cell that contain enzymes that can lyse, or digest, substances). Multiple enzyme deficiencies associated with I-cell disease lead to the accumulation of certain fatty substances (mucolipids) and certain complex carbohydrates (mucopolysaccharides) within the cells of many tissues of the body. The name…