fundoplication

fundoplication A surgical treatment for GERD. Usually a specific type of this procedure, called Nissen fundoplication, is performed, in which the upper part of the stomach is wrapped around the lower esophageal sphincter to strengthen this structure, prevent acid reflux, and repair a hiatal hernia. The procedure may be performed by laparoscopy. See also gastroesophageal…

fucosidosis

fucosidosis An inherited lysosomal storage disease characterized by lack of the enzyme fucosidase. Without fucosidase, there is accumulation of fucose in the tissues. Fucosidosis is an autosomal recessive disorder. The gene that is responsible for fucosidosis, FUCA1, is on chromosome 1. Fucosidosis in its most severe form can cause neurologic deterioration, growth retardation, visceromegaly (enlargement…