twin

twin One of two children produced in the same pregnancy. Twins can develop from one ovum (egg) or from two ova (eggs). Twins who develop from a single ovum are called monozygotic or identical twins. They have identical genomes. Twins who develop from two ova that are fertilized at the same time are called dizygotic…

Turner syndrome

Turner syndrome The most common sex chromosome disorder in females, characterized by short stature, webbed neck, broad shield-like chest, widespaced nipples, increased carrying angle at the elbow (cubitus valgus), short fourth finger, and malformations of the heart and aorta. The intelligence of those with Turner syndrome is usually within the normal range. Girls with Turner…

Turcot syndrome

Turcot syndrome A genetic disease characterized by polyps in the colon (large intestine) in addition to tumors in the brain. The polyps in the colon tend to become malignant. The brain tumors are also malignant. Skin abnormalities can also occur. Turcot syndrome is inherited in an autosomal recessive manner and can result from mutations in…

tumor registry

tumor registry Recorded information about the status of patients with tumors. Although a registry was originally the place where information was collected (in registers), the word registry has also come to mean the collection itself. A tumor registry is organized so that the data can be analyzed. For example, analysis of data in a tumor…

tumor necrosis factor

tumor necrosis factor One of multiple proteins capable of inducing necrosis (death) of tumor cells that possess a wide range of proinflammatory actions. Abbreviated TNF. TNF is a multifunctional cytokine with effects on lipid metabolism, coagulation, insulin resistance, and the function of endothelial cells lining blood vessels. Drugs that block the action of TNF have…