angiopathy

angiopathy Disease of the arteries, veins, and capillaries. There are two types of angiopathy: microangiopathy and macroangiopathy. In microangiopathy, the walls of small blood vessels become so thick and weak that they bleed, leak protein, and slow the flow of blood. For example, diabetics may develop microangiopathy with thickening of capillaries in many areas, including…

angioid streaks

angioid streaks Tiny breaks in the elastin-filled tissue in the retina in the back of the eye. Angioid streaks are seen in patients with pseudoxanthoma elasticum, a rare disorder of degeneration of the elastic fibers with tiny areas of calcification in the skin, retinae, and blood vessels, and they are visible during an examination using…

angioedema, hereditary

angioedema, hereditary A genetic form of angioedema. Persons with it are born lacking the enzyme C1 esterase inhibitor, a protein that normally inhibits the activation of a cascade of proteins. Without this inhibitor protein, angioedema occurs, resulting in recurrent attacks of swollen tissues, pain in the abdomen, and swelling of the voice box (larynx), which…