polycystic kidney disease

polycystic kidney disease An inherited disorder that is characterized by the development of innumerable cysts in the kidneys that are filled with fluid and replace much of the mass of the kidneys. The cysts eventually reduce kidney function, leading to kidney failure. Abbreviated PKD. PKD can be diagnosed via ultrasound imaging and via CAT or MRI scan. Treatment involves managing pain and treating infections, high blood pressure, and kidney failure. There are two major forms of PKD—autosomal dominant and autosomal recessive—that differ in many respects. See also polycystic kidney disease, autosomal dominant; polycystic kidney disease, autosomal recessive.