prostate enlargement
Prostate enlargement typically results from benign prostatic hyperplasia (BPH), a common, non-cancerous overgrowth of prostate tissue in aging men.
Causes and Differentiation
BPH stems from hormonal changes, particularly increased dihydrotestosterone (DHT), leading to glandular and stromal proliferation that compresses the urethra. While rare, enlargement can signal prostate cancer, necessitating PSA testing and digital rectal exam to distinguish.
Symptoms and Management
Symptoms include weak urine stream, frequent urination (especially nocturia), urgency, incomplete emptying, and straining. Treatments range from alpha-blockers (e.g., tamsulosin) and 5-alpha-reductase inhibitors (e.g., finasteride) for mild cases to minimally invasive procedures like UroLift or TURP surgery for severe obstruction.