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Raynaud’s phenomenon

Raynaud’s phenomenon A condition that results in discoloration of fingers and/or toes when a person is exposed to changes in temperature or emotional events and that occurs with a number of conditions, including rheumatic diseases such as scleroderma, rheumatoid arthritis, and systemic lupus erythematosus; hormone imbalance, including hypothyroidism and carcinoid imbalances; trauma, such as from frostbite or the use of vibrating tools; medications, particularly propranolol (brand name: Inderal), estrogens, nicotine, and bleomycin; and, uncommonly, cancer. When the discoloration occurs alone, it is called Raynaud’s disease. See also Raynaud’s disease.