diuretic, loop

diuretic, loop A diuretic that works by encouraging the loss of sodium (salt) and water by affecting sodium transport at the loop area of the kidneys. As the sodium is removed, it takes water with it. Loop diuretics are very strong, and they should be used only under constant medical supervision. They can deplete the electrolyte balance, cause dehydration, reduce blood volume, and worsen certain medical conditions. See also diuretic.