Guillain-Barre syndrome

Guillain-Barre syndrome A rare disorder characterized by a misdirected immune response against the peripheral nervous system associated with progressive symmetrical paralysis and loss of reflexes, usually beginning in the legs. In most cases of Guillain-Barre syndrome, the patient has a complete or nearly complete recovery. Guillain-Barre syndrome is not associated with fever. It usually occurs after a respiratory infection or may follow other triggering infections or events, including vaccinations. Treatment includes plasmapheresis, intravenous gamma globulin (IVIG) and supportive care. See also demyelination; Landry ascending paralysis.