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St. John’s wort
St. John’s wort A flowering plant, Hypericum perforatum, also known as Perforate St. John’s wort, that has long been believed to have medicinal qualities. There is some evidence that St. John’s wort may be useful in diminishing depression, but it is not a proven remedy for depression. Sun sensitivity, fatigue, stomach upset, and allergic reactions are among the side effects that have been reported in people taking St. John’s wort. This herb should be avoided in combination with other medications that can affect sun sensitivity, such as tetracycline (brand name: Achromycin), sulfa-containing medications, and piroxicam (brand name: Feldene). St. John’s wort can also cause headaches, sweating, and agitation when used in combination with serotonin reuptake inhibitor medications, such as fluoxetine (brand name: Prozac) and paroxetine (brand name: Paxil).