eosinophilic granuloma

eosinophilic granuloma A disease in which histiocytes multiply and attack the tissues, forming solitary or multiple eosinophilic granulomas. Eosinophilic granuloma predominantly affects children and young adults. It is the most common type of Langerhans cell histiocytosis. In patients with eosinophilic granuloma, granulomas may develop in bone, with overlying tender and sometimes warm areas of swelling with an inability to bear weight.