factor VIII

factor VIII A coagulation (clotting) factor. Classic hemophilia (hemophilia A) is due to a deficiency in factor VIII activity. Also known as antihemophiliac factor (AHF) or antihemophiliac globulin (AHG). Human factor VIII concentrates as well as recombinant (laboratory-produced) factor VIII are administered in the treatment of hemophilia A. See also hemophilia A.