granulosa cell tumor

granulosa cell tumor A tumor belonging to the sex cord-stroma group of tumors of the ovary, sometimes referred to as granulosa-theca cell tumors. Abbreviated GCT. GCTs commonly produce estrogen, and the accompanying symptoms of excess estrogen are often the reason for early diagnosis. Adult GCTs make up the majority of GCTs and usually occur in postmenopausal women. Most juvenile GCTs develop in individuals younger than 30 years and tend to recur within the first 3 years. Treatment of GCTs involves surgical removal, and the prognosis is generally good.