hemolytic disease of the newborn

hemolytic disease of the newborn Abnormal breakup of red blood cells in a fetus or newborn. Hemolytic disease of the newborn is usually due to antibodies made by the mother that are directed against the baby’s red blood cells. It is typically caused by Rh incompatibility (a difference between the Rh blood groups of mother and baby). Symptoms can be mild or severe and may include generalized swelling (hydrops fetalis), enlargement of the liver and spleen, jaundice, and anemia. Severe cases may lead to brain damage and/or death. Also known as erythroblastosis fetalis.