Dictionary

disorder, seasonal affective See seasonal affective disorder.

disorder, myeloproliferative A malignant disease of certain bone marrow cells, including those that give rise to the red blood cells, the granulocyte (types of white blood cells), and the platelets (which are crucial to blood clotting). The four major myeloproliferative disorders are polycythemia vera, myelofibrosis, thrombocythemia, and chronic myeloid leukemia (CML).

disorder, lymphoproliferative A malignant disease of the lymphoid cells and of cells from the reticuloendothelial system (lymph nodes and drainage tissues that clear inert particles within the body). A patient with lymphoproliferative disorder has proliferation and accumulation of lymphoid cells in the blood and marrow.

disorder, attention deficit See attention deficit disorder.

diskitis, tuberculous See tuberculous diskitis.

diskitis Inflammation of the disks between the vertebrae in the spinal column.

disk, choked See papilledema.

DISH Diffuse idiopathic skeletal hyperostosis.

diseases, rickettsial See rickettsial diseases.

disease, single gene A hereditary disorder caused by a change (mutation) in a single gene. There are thousands of single-gene diseases, including achondroplasia, Huntington’s disease, cystic fibrosis, sickle cell anemia, Duchenne muscular dystrophy, and hemophilia. Single-gene diseases typically describe classic simple Mendelian patterns of inheritance (as autosomal dominant, autosomal recessive, and X-linked traits), compared to…

disease, polygenic A genetic disorder caused by the combined action of more than one gene. Examples of polygenic conditions include some forms of coronary disease, hypertension, asthma, and diabetes. Because such disorders depend on the simultaneous presence of several genes, they are not inherited as simply as single-gene diseases. See also disease, single gene.

disease, obesity-related One of the diseases to which obesity predisposes, including type 2 diabetes; high blood pressure; stroke; heart attack; congestive heart failure; certain forms of cancer, such as prostate and colon cancer; gallstones and gall bladder disease; gout and gouty arthritis; osteoarthritis of the knees, hips, and lower back; sleep apnea; and Pickwickian syndrome.