claudication

claudication, intermittent Pain in the calf that comes and goes, typically felt while walking, and usually subsiding with rest. Intermittent claudication can be due to temporary artery narrowing due to vasospasm, permanent artery narrowing due to atherosclerosis, or complete occlusion of an artery to the leg. The prognosis is generally favorable because the condition often…

cirrhosis

cirrhosis, primary biliary A scarring liver disease caused by an abnormality of the immune system. Small bile ducts within the liver become inflamed and obliterated from scarring. Backup of bile causes intense skin itching and yellowing of the skin (jaundice). Lack of bile decreases absorption of calcium and vitamin D, leading to osteoporosis. See also…

circumcision, male

cirrhosis Liver disease characterized by irreversible scarring. Alcohol and viral hepatitis, including both hepatitis B and hepatitis C, are among the many causes of cirrhosis. Cirrhosis can cause yellowing of the skin (jaundice), itching, and fatigue. Diagnosis is suggested by physical examination and blood tests, and it can be confirmed by liver biopsy. Complications of…

circumcision, female

circumcision, male Surgery that removes the protective ring of loose skin (foreskin) that normally covers the glans of the penis. Circumcision dates back to prehistoric times, and it may be performed for religious or cultural reasons, or to promote cleanliness. Newborn circumcision decreases the risk of urinary tract infections and lowers the risk of sexually…