Pendred syndrome

Pendred syndrome A genetic disease that is characterized by congenital deafness, abnormalities of the inner ear, and goiter. Pendred syndrome is inherited in an autosomal recessive manner and is caused by mutations in the gene known as SLC26A4 (also referred to as the PDS gene) on chromosome 7. Also known as deafness with goiter, goiter-deafness syndrome, and thyroid hormone organification defect IIb.