sphingolipidosis

sphingolipidosis One of a group of hereditary diseases that involve overproduction or accumulation of fatty substances called sphingolipids in the brain and nervous system. See also Anderson-Fabry disease; Gaucher disease; GM1-gangliosidosis, histiocytosis, lipid; Krabbe disease; leukodystrophy; Tay-Sachs disease; Sandhoff disease.